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Fresh volleys of artillery fire were heard across many parts of the separatist stronghold of Donetsk in eastern Ukraine on Sunday, a Ukrainian government statement said, after Kiev warned again of rebel preparations for a fresh offensive.

Russia President Vladimir Putin said in a German television interview on Sunday that he is convinced it should be possible to find a way to resolve the crisis in Ukraine but added he was concerned about the threat of ethnic cleansing.

The world's top drugmakers have improved access to medicines in developing countries, according to a report on Monday, but their good work is undermined by a sorry record of unethical behavior.